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Gingival overgrowth is a pathologic event frequently associated with systemic use of certain medications and is often referred to as Drug-induced gingival overgrowth (DIGO). The degree of pathogenicity depends on the type of drug, its dose and duration; oral hygiene; individual susceptibility; genetic factors; and environmental influences. DIGO can be localized which may remain confined to papilla or can be generalized involving marginal gingiva that may completely cover the crowns of the teeth thereby causing aesthetic and functional problems. The first-line treatment of DIGO is substitution of related medications in combination with dental biofilm control and regular periodontal maintenance.

Drug-induced gingival overgrowth; drug substitution; systemic medication