Effect of Anesthetcs Containing Lidocaine and Epinephrine on Cardiovascular Changes During Dental Surgical Procedure

Neeraj Pant, A Singh


The purpose of this study was to evaluate cardiovascular changes during dental surgery using 2% lidocaine with 1:80 000 epinephrine. Eleven normotensive subjects, ranging from 18 to 56 years, were selected to undergo dental surgery in the jaw. They were monitored in the pre-, intra-, and postsurgical periods by continuous noninvasive automatic arterial pressure and cardiac frequency measurements taken every 2 minutes. Parameter scores were obtained for the following phases: P1, 15 minutes during preparation of the patient (control period); P2, before anesthesia; P3, immediately after anesthesia; P4, 2 minutes into anesthesia; P5, during incision and detachment; P6,. Individualized statistical analysis for each group during the pre-, intra-, and postoperative periods were performed by analysis of variance. The greatest variations in systolic pressure were increases of 2.29% during phase P2 and 2.59% in phase P5. Diastolic pressure decreased during phase P6 (2.58%) and increased in P6 (3.27%). The greatest changes in heart rate In normotensive subjects anesthetized with 2% lidocaine with epinephrine 1:80 000.


Cardiovascular changes, dental surgery, epinephrine, lidocaine, stress

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