| JNDA Vol. 10 No. 1 (January -June 2009) | |
An era of adjuvant therapies for oral pemphigus |
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| Shenoy N, Ongole R, Sumanth KN, Shenoy AK | |
Download Full Article  198.46KB |
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| Abstract | |
Pemphigus vulgaris (PV) is an autoimmune disease characterized by blistering and erosions on skin and mucous membranes due to acantholysis. It is the second most common chronic bullous dermatosis; next to bullous pemphigoid. The use of corticosteroids since the 1950s has reduced the mortality from 60% - 90% to about 30%, but it still carries significant morbidity. The mainstay of treatment even today remains to be corticosteroids with or without other adjuvant therapies such as immunosuppressive agents, anti-inflammatory agents and immunomodulatory drugs. This paper emphasizes on popular adjuvant therapies that can help achieve long term remission even in case of recalcitrant lesions of pemphigus vulgaris. |
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| Keywords | |
Corticosteroid therapy, Pemphigus vulgaris |
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