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Drug-induced gingival enlargement is a well documented unwanted side effect within the literature. It has been associated with the use of three different types of pharmaceutical agents, including phenytoin, cyclosporine and calcium channel blocking agents. Amlodipine belongs to the dihydropyridine-derived calcium blocking agents that may cause the side effect of drug-induced gingival enlargement. Treatment options include meticulous plaque control, and in severe cases, gingivectomy. Gingival enlargement can be prevented with meticulous plaque control or avoidance of the offending medication. This paper presents a rare case of amlodipine-induced gingival overgrowth in a 40-year-old male patient. The treatment aspect included Phase-1 therapy, substitution of the drug and the maintenance and supportive therapy resulting in excellent clinical outcome.

Amlodipine, Gingival enlargement, Non surgical