| JNDA Vol. 11 No. 1 (January - June 2010) | |
The role of neural crest cells and homeobox genes in craniofacial development |
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| Bajracharya M, Mishra P, Bhattarai P | |
Download Full Article  150.34KB |
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| Abstract | |
The role of neural crest cells in the development of craniofacial development has been a topic of research for the molecular biologist for decades. With the discovery of the homeobox genes, many research and investigations have shown that there is a genetic control for the patterning of the craniofacial region. With the identification of more different types of homeobox gene along with the transcription factors, it is becoming clearer that the homeobox genes have greater role than previously thought. With advancement of the research techniques, more insights of the role of these genes have been explored. These genes in fact are found to be the regulators and thus the master genes of the head and face. So it is now transparent that there is a genetic domination over the development and the patterning of the head and facial region through these genes. This review article tends to give a simplified overview of the role of neural crest cells and homeobox genes in the development of the craniofacial complex. |
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| Keywords | |
Neural crest cells, Homeobox genes, Craniofacial development |
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