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Orthodontic treatment involves the application of force which has complex interaction with the paradental tissues. The Orthodontists should have a thorough understanding of biological aspects of orthodontic force (OF) and orthodontic tooth movement (OTM). This understanding will help us to apply appropriate mechanics so that we can maximize the rate of tooth movement with healthy biology and comfort to the patient. This review article attempts to compile the published articles related to OTM and amalgamate them so as to formulate a clear understanding of biology of OTM in a concise form. The articles were searched by conduction of an electronic search through Pub Med and Hinari and references from citations within the articles.

Orthodontic tooth movement, Biological response