| JNDA Vol. 18 No. 2 (July - December 2018) | |
Piroxicam versus Ibuprofen-Paracetamol Combination in Lower Third Molar Surgery |
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| Dr. Bandana Khanal, Dr. Sandhya Joshi, Dr. Ishfa Banu Haque, Dr. Kishor Bhandari, Dr. Pramod Kumar Koirala | |
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| Abstract | |
Introduction: Lower third molar has served as a suitable model for assessment of inflammation for many studies. Various drugs and their combination have been used to test their effect on this model. Objective: Main objective of this study was to compare the efficacy of Piroxicam with the widely prescribed Ibuprofen Paracetamol combination. Materials and Method: This single center, single operator assisted comparative study had 70 patients divided equally into both the groups. Inflammatory parameters such as trismus and swelling were measured for evaluation at different time intervals. Result: The statistical results of ANOVA showed similar pattern for both trismus and swelling. Though there was no significant difference (p>0.05) on the 7th day, the results of the second day significantly favoured (p<0.005)Piroxicam. Conclusion: Both the group of drugs showed equivalent efficacy after 1 week, though the immediate post-op benefit of Piroxicam and its ease of use cannot be overlooked.
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| Keywords | |
Comparison; ibuprofen-paracetamol combination; lower third molar extraction; piroxicam dispersible tablets. |
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