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Introduction: Dentinal hypersensitivity (DH) is a common painful dental condition which can cause extreme discomfort to patient for which dental treatment is sought.

Objective: To evaluate the efficacy of GC Tooth Mousse and Clinpro XT Extended contact varnish as compared to Gluma desensitising agent.

Materials and Method: A randomised, double-blind, single-centre controlled clinical trial was conducted at Conservative Dentistry and Endodontics Unit, Dental Department, Bir Hospital from January 2018 to June 2019 after taking approval from the institutional review board. A total of 105 teeth from 90 patients aged 20-60 years, with complaint of hypersensitivity were randomly allocated into three treatment groups, Group A: Gluma desensitiser, Group B: GC Tooth Mousse, Group C: Clinpro XT Extended contact varnish after taking an informed consent. Visual Analogue Scale (VAS) was used to record degree of hypersensitivity based on patient’s response to tactile and air blast stimuli. Scores were recorded at base line, immediately after application of desensitising agent, at one month, three months and six months. Data were analysed using SPSS v.16 and Microsoft Excel. Mean VAS scores were calculated.

Result: Clinpro XT produced a significant reduction in mean VAS dentinal hypersensitivity score compared to Gluma and GC Tooth Mousse with both tactile and air blast stimuli. There seem to be no statistically significant difference in DH reduction between GC Tooth Mousse and Gluma group.

Conclusion: Clinpro XT was significantly better than other two desensitising agents at all intervals up to six months for both tactile and air stimuli.

Clinpro XT; dentinal hypersensitivity; GC tooth mousse; Gluma.