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Introduction: Intra-coronal bleaching, though is an established, simple, cost-effective and conservative method of improving the shade of root canal treated discoloured anterior teeth, have shown some effects on microhardness of enamel and dentin, biomechanical properties of dental hard tissues and also the ultrastructure and mineral content of dentin. This research is conducted to evaluate the change in dentin micro-hardness using intra-coronal bleaching agents in combinations.

Objective: The aim of this study was to evaluate and compare the microhardness of human dentin following the use of intra-coronal bleaching agents in various combinations.

Materials and Method: A total of 52 samples of extracted maxillary central incisors were divided into four groups of 13 each. Group 1: Sodium perborate + 3% Hydrogen peroxide, Group 2: Sodium perborate + 10% Carbamide peroxide, Group 3: 10% Carbamide peroxide +3% Hydrogen peroxide and Group 4: Control group (distilled water). Intra-coronal bleaching procedure was carried out in all the sample teeth and dentin microhardness was tested using Knoop indenter.

Result: One-way analysis of variance was carried out for testing significance of the differences in the mean values for multiple group comparisons. All results were considered statistically significant if p

Conclusion: Hydrogen peroxide 3%, carbamide peroxide 10% and sodium perborate in the tested combinations are safe to use as intra-coronal bleaching agents in respect to their action on dentin microhardness. 

Carbamide peroxide; dentin microhardness; hydrogen peroxide; maxillary central incisors; sodium perborate.